Application List

No.

Name

Institution

Project Name

Patient No.

Approval date

103001

Lin-Tsing Chen

Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital

Tumor Biology of Hepatocellular Carcinoma

90

20141226

104002

Su-Fang Lin

National Institute of Cancer Research, National Health Research Institutes, Taiwan

FGFR2 gene fusion in Taiwanese intrahepatic cholangiocarcinoma tissues

90

20150306

104003

Yoa-Pu Hu

Department of Pharmacy, National Defense Medical Center

Function and expression of drug transporters dictate the different rosuvastatin systemic exposure between Asians and Caucasians

40

20150508

104004

Dar-In Tai

Gastroenterology and hepatology, Chang Gung Memorial Hospital

Human genetic polymorphism in therapeutic response of chronic hepatitis B

1000

20150731

104005

Sen-Yung Hsieh

Chang Gung Memorial Hospital

In vivo functional genomics to decipher the genes/mechanisms orchestrating hepatoma invasion

180

20150731

104006

Yun-Ru Liu

Joint Biobank, Taipei Medical University

The association analysis of a histone mRNA as a new biomarker of HCC recurrence

92

20151005

104007

Hsu Shih-Hsien

KMU

To explore the regulatory effect of aryl hydrocarbon receptor (AhR) on initiation and enhance role of oncoprotein ISX in human hepatocellular carcinoma (HCC)

200

20151005

104008

Pei-Jer Chen

Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine

Development of new treatment and biomarker for hepatocellular carcinoma: from woodchuck to human (3/3)

120

20151005

104009

Wan-long Chuang

Kaohsiung Medical University Chung-Ho Memorial Hospital

HCV infection affects on growth hormone signaling pathway in liver diseases and hepatocellular carcinoma progression

200

20151207

105010

Yi-Hsiang Liu

Chiung-Chi Cheng

Chang Bing Show Chwan Memorial Hospital

Differential expression of the cytoskeleton proteins and the plectin in human hepatocellular carcinoma versus liver cells and in cholangicarcinoma versus bile duct epithelium

120

20160121

105011

Yuh-Shan Jou

Institute of Biomedical Sciences ,Academia Sinica

Dissecting molecular mechanisms of PSPC1 overexpression driven cancer EMT, stemness and tumor metastasis.

200

20160121

105012

Pei-Jer Chen

Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine

Development of new treatment and biomarker for hepatocellular carcinoma: from woodchuck to human (3/3)

120

20160121

105013

Yi-Hsiang Huang

Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital

The Role of Tid1 Expression in Behavior and Prognosis of hepatocellular Carcinoma

200

20160325

105014

Chiun Hsu

National Taiwan University Hospital

Incorporation of genomic and immunological studies for biomarker identification for hepatocellular carcinoma

600

20160325

105015

Jui-Hsiang Hung

Department of Biotechnology, Chia Nan University of Pharmacy and Science

To investigate the effect of nucleobindin-2 overexpression by endoplasmic reticulum stress on hepatocellular carcinoma treatment

120

20160503

105016

Kwang-Huei Lin

Graduate Institutes of Biomedical Sciences, Chang Gung University

Characterization the physiological significance of angiogenesis associated gene regulated thyroid hormone

160

20160503

105017

Shih-Feng Tsai

Institute of Molecular and Genomic Medicine, National Health Research Institutes

Translational research on genomic variations in liver cancer

250

20160503

105018

Alice L. Yu

Institute of Stem Cell and Translational Cancer Research, Linkou Chang Gung Memorial Hospital

Tumor Biology of Hepatocellular carcinoma

90

20160725

105019

I-Cheng Lee

Division of Gastroenterology and Hepatology, Department of Medicine ,Taipei Veterans General Hospital

The Role of Host Immune Regulators and Tumor Microenvironment in the Prognosis of Hepatocellular Carcinoma

200

20160919

105020

Yu-Tsung Shih

Institute of Cellular and System medicine, National Health Research Institutes

Unrevealing the Metabolic Abnormalities of Endothelial Cells in Response to the Angiogenic Niche Composed by Endothelial Progenitors and Hepatocarcinoma Cells

24

20160919

105021

Shiou-Hwei Yeh

Dept. of Microbiology, College of Medicine, National Taiwan University

The distribution trend of Glypican-3 expression in hepatocellular carcinoma

120

20160919

105022

Li Ching Li

Shuang Ho Hospital, Taipei Medical University

Investigation of nicotine/cigarette-smoke promotes metastasis of hepatocellular carcinoma through nAChR and pre-clinically evaluation of correlation between smoking and hepatocellular carcinoma

180

20161128

105023

Chiun Hsu

National Taiwan University Hospital

Incorporation of genomic and immunological studies for biomarker identification for hepatocellular carcinoma

800

20161128

106024

Hsieh, Shie-Liang

Genomics Research Center, Academia Sinica

Liver and plasma C-type lectin 18 (CLEC18) expression in hepatitis B and C virus infected patients

260

20170209

106025

Hsiung, Chao Agnes

Institute of Population Health Sciences, National Health Research Institutes

Using EGFR mutation status and germline genetic variants jointly to make decision for treating late-stage lung adenocarcinoma patients - a prospective study

220

20170209

106026

Yi-mimg Chen

Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University

A study of the epigenetic regulation of GNMT gene expression and the role GNMT plays in the control of global DNA methylation

80

20170209

106027

Jung-Jyh Hung

Division of Thoracic Surgery, Taipei Veterans General Hospital

Identification of genes related to metastasis and their regulating mechanisms in lung cancer by combination of pathological subtypes and gene expression in microarray (II)

120

20170209

106028

Pei-Jer Chen

Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University

Taiwan Research Biosignature Network on Patients at High Risk of Hepatocellular Carcinoma (TARGET-HCC)

60

20170419

106029

Hsien-Chung Yu

Division of Gastroenterology and Hepatobiliary, Department of Internal Medicine, Kaohsiung Veterans General Hospital

The correlation between serum BioFibroScore, Pre-S Deletion and Histological Fibrosis in Chronic Hepatitis B Patients with Hepatocellular Carcinoma Receiving Curative Resection

150

20170419

106030

Tung-Hung Su

Internal Medicine, National Taiwan University Hospital

Clinical implications of immunophenotypes in liver fibrosis and hepatocellular carcinoma

150

20170612

106031

Shih-Feng Tsai

Institute of Molecular and Genomic Medicine, National Health Research Institutes

Flagship program of precision medicine for Asiapacific Biomedical Silicon Valley

200

20170811

106032

Chau-Ting Yeh

Liver Research Center, Chang-Gung Memorial Hospital

Clinical and molecular characterization of hepatocellular carcinoma carrying distinct patterns of HBV S gene truncation mutations

11

20170612

106033

Yan-Hwa Wu Lee

Department of Biological Science and Technology, National Chiao-Tung University

Functional roles of DDX3 in regulating exosome biogenesis and its therapeutic potential on hepatic tumorigenesis

75

20170811

106034

Chau-Ting Yeh

Liver Research Center, Chang-Gung Memorial Hospital

Clinical and molecular characterization of hepatocellular carcinoma carrying distinct patterns of HBV S gene truncation mutations

200

20170811

106035

Chia-Hung Yen

Graduate Institute of Natural Products, Kaohsiung Medical University

A study of the role of redox state in the development of sarcomatoid hepatocellular carcinoma and its application in antiliver cancer drug discovery

120

20171020

106036

Jun-Yang Liou

Institute of Cellular and System Medicine, National Health Research Institutes

To investigate the role of AKR1B10 expression and metabolism in regulating epithelial-mesenchymal transition and drug resistance of hepatocellular carcinoma

150

20171222

106037

Li-Fen Shen

Drug Development  Division, TaiRx,Inc.

A Pilot Study of Tumor Prognostic Biomarker in Hepatocellular Carcinoma

120

20180205

106038

Jun-Yang Liou

Institute of Cellular and System Medicine, National Health Research Institutes

To investigate the role of AKR1B10 expression and metabolism in regulating epithelial-mesenchymal transition and drug resistance of hepatocellular carcinoma

150

20180205

107039

Jyh-Lyh Juang

Institute of Molecular and Genomic Medicine,National Health Research Institutes

Identification of potential mechanism for liver cancer in tumor tissue

50

20180409

107040

Mei-Hwei Chang

Pediatrics,National Taiwan University College of Medicine

Long-term Follow-up of Chronic Hepatitis B Virus Infection from Mother-to-Infant Transmission to Adult Life

50

20180409

107041

Jinn-Moon Yang

Institute of Bioinformatics and System Biology,National Chiao Tung Tung University

Intelligent Computing Precision Medical and Drug Development Platform – Integrated dynamic systems biology models to study the mechanisms between diabetes mellitus and liver cancer for developing biomarkers and drugs

120

20180409

107042

Yan-Hwa Wu Lee

Department of Biological Science and Technology, National ChiaoTung University

Center for Intelligent Drug Systems and Smart Bio-devices, IDS2B

30

20180409

107043

Yue-Liang Guo

National Institute of Environmental Health sciences,National Health

Research Institute

Air pollutants and hepatocellular carcinoma survival

1000

20180927

107044

Jui-Hsiang Hung

Department of Biotechnology,Chia Nan University of Pharmacy and Science

To investigate the mechanism of endoplasmic reticulum stress-induced nucleobindin-2 expression and its effect on the treatment of liver cancer

120

20180626

107045

Pei-Jer Chen

Graduate institute of Clinical Medicine,College of Medicine,National Taiwan University

Taiwan Research Biosignature Network on Patients at High Risk of Hepatocellular Carcinoma(TARGET-HCC)

50

20180626

107046

Hsu Shih-Hsien

Graduate Institute of Medicine,Kaohsiung Medical University

To explore the potential regulatory mechanism and clinical outcomes of epigenetic modulator, PCAF, on oncogenic transcriptional complex, ISX-Brd4-RNA pol II complex in lung cancer

50

20180829

107047

Hsiung CA

Institute of Population Health Sciences,National Health Research Institutes

Biomarker Development for Lung Adenocarcinoma Risk Prediction and Drug Response

300

20180829

107048

Jyh-Lyh Juang

Institute of Molecular and Genomic Medicine, National Health Research Institutes

Indentification of potential mechanism for liver cancer in tumor tissue

40

20181220

107049

Mei-Hwei Chang

Prediatrics,National Taiwan University College of Medicine

Long-term Follow-up of Chronic Hepatitis B Vitus Infection from Mother-to-Infant Transmission to Adult Life

150

20181220

107050

Ma,Wen-Lung

Graduate Institute of BioMedical Sciences,China medical university

Study of the metabolic syndrome-related VLDL and VLDLR roles in hepatocellular carcinoma

225

20181220

108051

Tzu-Ling Tseng

Bio Preventive Medicine Corp.

Cancer biomarkers development

60

20190227

108052

Chi-Ying Huang

Institute of Biopharmaceutical Sciences,National Yang-Ming University

The prognostic correlation of exosomal GPC3 level at diagnosis,surveillance and survival of patients with hepatocellular carcinoma

50

20190227

108053

Chao-Wei Hsu

Division of Gastroenterology and Hepatology, Chang-Gung Memorial Hospital

Clinical and Functional Significance of infections of Genetically Different Hepatitis Delta Virus

300

20190227

108054

Mei-Hwei Chang

Pediatric,National Taiwan University College of Medicine

Long-term Follow-up of Chronic Hepatitis B Virus Infection from Mother-to-Infant Transmission to Adult Life

100

20190227

108055

Yan-Hwa Wu Lee

Department of Biological Science and Technology, National Chiao Tung University

Center for Intelligent Drug Systems and Smart Bio-devices, IDS2B

50

20190424

108056

Shih-Feng Tsai

Institute of Molecular and Genomic Medicine, National Health Research Institutes

Translational research on genomic variations in liver cancer

150

20190424

108057

Ling-Yueh Hu

Laboratory of Translational Medicine Office, Development Center for Biotechnology

Explore the expression and distribution of the immune checkpoint related proteins in normal liver tissue

40

20190625

108058

George Wei

Clinical Project Management Dep. ACT Genomics Co., Ltd.

To Study the Association between Mutational Spectrum/Tumor Microenvironment and Prognosis in HCC/CC Using Archived Specimens

300

20190625

108059

Ting-Fen Tsai

Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University

Development of novel therapeutics for non-alcoholic fatty liver diseases (NAFLD) and steatohepatitis (NASH)

170

20190820

108060

Yang-Hsiang Lin

Liver Research Center, Chang Gung Memorial Hospital, Linkou

Characterization of LOC731656 functions in human hepatocellular carcinoma and its clinical significance

80

20190820

108061

Lee, Mei-Hsuan

Institute of Clinical Medicine, National Yang Ming University

DNA methylation profiling, antigen representation of HLA and associated risk for hepatocellular carcinoma

900

20191007

108062

Sen-Yung Hsieh

Dept. of Gastroenterology & Hepatology, Linkou Chang Gung Memorial Hospital

Decipher genomic and epigenomic alternations in the liver and digestive cancers

108

20191007

108063

Yan-Hwa Wu

Lee

Department of Biological Science and Technology, National Chiao Tung University

Center for Intelligent Drug Systems and Smart Bio-devices, IDS2B

30

20191213

108064

JAW-CHING  

WU

Institute of Clinical Medicine, National Yang Ming University

Investigating the regulatory mechanism of glycosphingolipids in Hepatitis B virus-transgenic mice and human liver cancer specimens for the development of novel diagnostic and therapeutic strategies for Hepatocellular carcinoma

680

20200213

108065

Sheng-Hui Lan

Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University

Physiologic and pathologic roles of FUS for microRNA turnover by selective autophagy

16

20200213

109066

Jun-Yang Liou

Institute of Cellular and System Medicine, National Health Research Institutes

Characterization of HIOMT isoform for 5-MTP biosynthesis and its defect in cancer

150

20200422

109067

Shun-Fa Yang

Department of Medical Research, Chung Shan Medical University Hospital

Study of the LncRNA genetic variants in hepatocellular

carcinoma

400

20200422

109068

Chao-Wei Hsu

Division of Gastroenterology and Hepatology, Chang-Gung Memorial Hospital

Clinical and Functional Significance of Infections of Genetically Different Hepatitis Delta Virus

8

20200422

109069

Tsai, Jih-Jin

Tropical Medicine Center, Kaohsiung Medical University Chung-Ho Memorial Hospital

Research and development of COVID-19 precision diagnostics

30

20200422

109070

Ho Ming-Chih

Surgery, National Taiwan University Hospital

Specific HBV-human chimera DNA as a novel biomarker for predicting the outcome of HCC after transplantation (2)

136

20200520

109071

 Chao-Cheng Haung

Pathology, Kaoshiung Chang Gung Memorial Hospital

Investigating the Role of Delta-like 1 Homolog (DLK1) in T Cell Immune Surveillance of Hepatocellular Carcinoma

80

20200520

109072

Kuo-Shyang Jeng

General Surgery, Far Eastern Memorial Hospital

To investigate the role of inhibition of sonic Hedgehog signaling pathway in increasing the sensitivity of doxorubicin in hepatocellular carcinoma-an in vitro and in vivo study

20

20200520

109073

Lin Ming-Tsung

Kaohsiung Chang Gung Memorial Hospital

Biomarkers analysis for hepatocellular carcinoma and liver fibrosis

20

20200520

109074

Kuo Kuang-Tai

Thoracic surgery, Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare

Targeting the BTK-ITK axis as a potential therapeutic strategy for overcoming drug resistance and inhibiting brain metastasis in lung cancer

48

20200520

109075

Jian-Xun Chen

Thoracic Surgery, China Medical University Hospital

Exploring the clinical significance of multi-omic markers of lung cancer

75

20200610

109076

Kelvin Kunchih 

Tsai

Graduate institute of Clinical Medicine / Division of Gastroenterology, Department of Internal Medicine, Taipei Medical University / Taipei Municipal Wan Fang Hospital

The role of ASPM-Wnt signaling in hepatoma cancer stemness and progression and the development of the related nano- and gene-therapy

100

20200610

109077

Kao, Ming-wei

Thoracic Surgery, E-Da Hospital

Gene expressions of vasculogenic mimicry in lung

adenocarcinoma

50

20200610

109078

CHEN YAW-

SEN

Department of Surgery, E-Da Hospital

To study amino-acid-dependent GATORC1/mTORC1 signaling in the development of hepatocellular carcinoma

90

20200610

109079

Chang Wei Li

AllBio Science, Inc

The COVID-19 rapid test development

35

20200610

109080

Guan-Da Syu

Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University

Antibody Profiling of COVID-19 Using Coronavirus Protein and Peptide Microarray

110

20201028

109081

Liang-Tzung Lin

Microbiology and Immunology, Taipei Medical University

Establishment of SARS-CoV-2 Pseudoparticle System as Diagnostic and Therapeutic Testing Platform

10

20200714

109082

Chen, Shao-Yuan

Laboratory of Translational Medicine Office, Development Center for Biotechnology

Explore the impact of signal transduction factors in tumor progression

90

20200714

109083

Yen-Hui Chiu

Department of Technology, Union Clinical Laboratory

Analytical validation of commercial mutation detection systems in clinical specimens

100

20200714

109084

Hsieh, Ching-Hua

Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital

Using circulating biomarkers to identify the patients with hepatocellular carcinoma-based on the samples from National Biobank Consortium of Taiwan

50

20200714

109085

Yen-Hsu Chen

Medical School, Kaohsiung Medical University

Development of a rapid diagnosis CMOS of 2019-nCoV

55

20200714

109086

Weng Ching-Fu

Respiratory Therapy & Chest medicine, Hsinchu Cathay General Hospital

The role of CAR expression in human lung cancer and analysis the mechanism of respiratory associated virus infection in lung epithelial cell tumorigenesis

100

20200714

109087

Wen-Chi, Yang

Hematology and medical oncology, E-Da hospital

Immune landmark in local limited HCC and advanced HCC

210

20200921

109088

Pei-Ing Hwang

Digital Health Planning Group, Development Center for Biotechnology

Development of Biomarkers for Precision Medicine with Big Data Analyses

50

20200812

109089

Han-Shui Hsu

Division of Thoracic Surgery, Taipei Veterans General Hospital

The Role of Collagen XVII in the Pluripotent Gene Expression and Metabolic Reprogramming of Lung Cancer Stem Cells

100

20200812

109090

Hung-Wei Yang

Institute of Medical Science and Technology, National Sun Yat-sen University

A ultrasensitive EasyVial for rapid diagnostic test of viral infections

90

20200714

109091

Chang Wei Li

AllBio Science, Inc

The COVID-19 rapid test development

80

20200714

109092

Cheng-Yi Chen

Department of Cell Biology and Anatomy, National Cheng Kung University

Investigate the molecular mechanism of protein tyrosine phosphatase IVA3 (PTP4A3) in cisplatin/doxorubicin chemoresistance of hepatocellular carcinoma

160

20200812

109093

Chih-Yang Huang

Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Study the genes and molecular mechanisms affecting of colorectal cancer, lung cancer and liver cancer

39

20200812

109094

Chang Yu Ping

Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital

Immune biomarkers and pathology correlation in lung adenocarcinoma patients with epidermal growth factor receptor gene mutation and brain metastasis

60

20200812

109095

Po-Hao Feng

Pulmonary Medicine, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare

The role and mechanism of CD155/TIGIT in MDSC/TAM induced NK cell dysfunction -A link to lung cancer resistance to immune checkpoint blockade

40

20200812

109096

Tai-Tong Wong

Neurosurgery, Taipei Medical University Hospital

Integration of treatment strategies and molecular diagnosis for childhood cancers in Taiwan

5

20200812

109097

Xu, Jia-quan

Research and Inspection Group Biopharmaceutical Section, Taiwan Food and Drug Administration

Preparation of SARS-CoV-2 antibodies for COVID-19 vaccine candidates evaluation

40

20200812

109098

Ching-Wei Tsai

Department of Biosensing Development, Helios Bioelectronics Inc.

Detection of protein from COVID-19 serum samples by semiconductor-based biosensors

10

20200812

109099

Yan-Hwa Wu

Lee

Department of Biological

Science and Technology, Tung University

Center for Intelligent Drug Systems and Smart

Bio-devices, IDS2B

50

20200921

109100

Tan Tse-Hua

Immunology Research Center, NHRI

Signaling Pathways as Therapeutic Targets for COVID-19 infection

60

20201028

109101

Lung-Wen Tai

R&D Division, Agnitio Science & Technology, Inc.

BioIC SARS-CoV2 IgG/IgM Detection Kit-Performance Evaluation

100

20200921

109102

Evelyn Chen

BioMedical Sensing Business Division, DELBIO, INC.

COVID-19 IgG/IgM Rapid Test Clinical Trials

180

20200921

109103

Pei-Min Chen

Pre-clinical and clinical study Dept.,United Biomedical ,Inc.,Asia

Analysis of immunogenicity in COVID-19 convalescent serum samples

30

20200921

109104

Shu-Chen Kuo

National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes

Antibody responses to SARS-CoV-2 in patients with COVID-19

20

20200921

109105

Jyh-Lyh Juang

Institute of Molecular and Genomic Medicine, National Health Research Institutes

Identification of potential mechanism for alcohol-induced liver cancer in tumor tissue

48

20201028

109106

Jia-Chuan Hsu

Section of Biologics, Division of Research and Analysis, Taiwan Food and Drug Administration, Ministry of Health and Welfare

Preparation of SARS-CoV-2 antibodies for COVID-19 vaccine candidates evaluation

55

20201028

109107

Der-Yuan Chen

Division of Rheumatology and Immunology, China Medical University Hospital

The associations of hyperferritinemia with disease pathogenesis and COVID-19 infection in rheumatic patients

30

20201119

109108

Ching-Wei Tsai

Department of Biosensing Development, Helios Bioelectronics Inc.

Detection of protein from COVID-19 serum samples by semiconductor-based biosensors

105

20201119

109109

Zhong-Zhe Lin

Medical Oncology, National Taiwan University Cancer Center

Define the clinicopathologic significance of CpG island methylator phenotype in intrahepatic cholangiocarcinoma

100

20201119

109110

Shih-Jen Liu

National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes

Development of quantitative rapid test for Covid-19 disease

70

20201119

109111

Hsiang-Tsui Wang

Department of Pharmacology, National Yang-Ming University

Using nano-imaging approaches to reveal the interplay of SARS-CoV-2 spike protein with cellular receptors and SARS-CoV-2 spike protein-induced cellular responses

90

20201230

109112

Yahui Huang

Division of Human Pharmaceuticals and Diagnostics, Schweitzer Biotech Company Ltd.

Cross Reactivity Study of SBC COVID-19 IgG ELISA Kit

80

20201230

109113

Joe Yeh

Office of the CEO, English aether AI Co., Ltd.

AI model of ER、PR、HER-2、Ki-67 in breast cancer

10

20201230

110114

Mei-Ren Pan

Graduate Institute of Clinical Medicine, Kaohsiung Medical University

The role of epigenetic modifying enzymes and inhibitors in personalized therapy of breast cancer patients

2

20210222

110115

Yu-Jiun Chan

Division of Microbiology, Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital

Study of the association among HCMV US28 genotypes and outcome of colorectal patients

7

20210222

110116

Andrew Yueh

Institute of biotechnology and pharmaceutical research, National Health Research Institute

Development of next-generation biologics for cancer & immunotherapy therapy

Item 1. Development of next-generation antibody drug conjugates

40

20210222

110117

Jia-Chuan Hsu

Section of Biologics, Division of Research and Analysis, Taiwan Food and Drug Administration, Ministry of Health and Welfare

Preparation of SARS-CoV-2 antibodies for COVID-19 vaccine candidates evaluation

67

20210222

110118

Tzou-Yien Lin

Department of Pediatrics, Chang Gung Memorial Hospital

A haemagglutination test for rapid detection of antibodies to SARS-CoV-2

100

20210421

110119

Guann-Yi Yu

National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes

RNA viral infection and pathogenesis

35

20210421

110120

Yi-Ming Arthur Chen

Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University

Using TLCN unlink samples to evaluate the application of novel circulating microRNAs on hepatocellular carcinoma diagnostic and prognostic

100

20210625

110121

Guan-Da Syu

Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University

Antibody Profiling of COVID-19 Using Coronavirus Protein and Peptide Microarray

60

20210625

110122

Hsiang-Ju Chen

Molecular Virology, LumiSTAR Biotechnology, Inc.

Development of rapid SARS-CoV-2 Neutralizing Antibody Serologic Detection Kit

160

20210625

110123

Kent Yeh

Product development department, Avirovac

SARS-CoV-2 Neutralization Antibody ELISA Development

60

20210625

110124

Yi-Ming Arthur Chen

Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University

Study to evaluate the application of novel circulating microRNAs on diagnosis and prognosis of lung cancer

200

20210820

110125

Der-Yuan Chen

Division of Rheumatology and Immunology, China Medical University Hospital

The association of anti-cytokine antibodies with disease activity parameters and infection in rheumatic patients

120

20210820

110126

Huang, Yen Chun

Operation management, Marker Exploration Corp.

Clinical Utility of Plasma Cancer Proteomic Profile for Early Detecting Lung Cancer

105

20210820

110127

Ching-Fu Weng

Division of Pulmonary Medicine, Hsinchu Cathay General Hospital

Detection of airway commensal microbiome in association with lung cancer promotion by whole genome and whole-transcriptome sequencing analyses

100

20210820

110128

Pei-Yi Chu

Department of Pathology, Show Chwan Memorial Hospital

To investigate the malignant role of LGR5 in triple-negative breast cancer and develop LGR5 targeted chemotherapy aptamer by Magnetic-Assisted Rapid Aptamer Selection (MARAS)

12

20211007

110129

Po Sheng Yang

General Surgery, MacKay Memorial Hospital

Study and Validation for Epstein-Barr virus infection, genes mutation and outcome in breast cancer patients

2

20211007

110130

Hsin-Chou Yang

Institute of Statistical Science, Academia Sinica

Establishing NGS analytical model for understanding the infectious program of SARS-CoV-2

200

20211007

110131

Yahui Huang

Division of Human Pharmaceuticals and Diagnostics

Clinical Agreement Study of SBC COVID-19 ELISA

80

20211007

110132

Ruey-Hwa Chen

Institute of Biological Chemistry, Academia Sinica

The roles of long noncoding RNA LINAT in tumor progression

100

20211007

110133

Tsai, Jih-Jin

Tropical Medicine Center, Kaohsiung Medical University Chung-Ho Memorial Hospital

Research and development of COVID-19 precision diagnostics

120

20211217

110134

Kwang-Huei Lin

Graduate Institutes of Biomedical Sciences, Chang-Gung University

The clinical significance of thyroid hormone-regulated non-coding RNAs

120

20211217

110135

Ding-Ping Sun

Department of Surgery, Chi Mei Medical Center

Clinical impact and carcinogenic mechanism of NCAPG overexpression in colorectal cancer

36

20211217

110136

Mei-Ren Pan

Graduate Institute of Clinical Medicine, Kaohsiung Medical University

The role of epigenetic modifying enzymes and inhibitors in personalized therapy of breast cancer patients

2

20211217

110137

Been Ren Lin

Department of Surgery, National Taiwan University Hospital

Investigation of molecular mechanism and clinical significance of ATMIN (ataxia telangiectasia mutated interactor) in colorectal cancer with MSS (microsatellite stable) status

10

20211217

110138

Chih-Hao Huang

Breast Surgical Oncology, China Medical University Hospital

Exploring the clinical significance of multi-omic markers of young Taiwanese women with triple-negative breast cancer

10

20211217

110139

Sheng-Chi Chang

Colorectal Surgery, China Medical University Hospital

Exploring the clinical significance of multi-omic markers of mucinous colorectal adenocarcinoma

30

20211217

110140

Tsu-Yi Chao

The Graduate Institute of Clinical Medicine, Taipei Medical University

Investigating the role of BTK/HER2 signaling as a therapeutic target for restoration of T cell function and reversal of Trastuzumab resistance in HER2+ Breast cancer

8

20211217

110141

Yu-Jiun Chan

Division of Microbiology, Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital

Study of the association among HCMV US28 genotypes and outcome of colorectal patients

2

20211217

110142

Ling-Ming Tseng

Comprehensive Breast Health Center, Taipei Veterans General Hospital

Using RNA sequencing to predict the therapeutic response and explore the resistance mechanism for immune checkpoint blockade therapy in patients with triple-negative breast cancer

12

20211217

111143

Jun-Yang Liou

Institute of Cellular and System Medicine, National Health Research Institutes

To investigate the role of Nik-related kinase in regulating tumor progression of lung adenocarcinoma (LAC)

60

20220223

111144

Tsai-Ling Liao

Department of Medical Research,Taichung Veterans General Hospital

The pathogenic role of extracellular vesicles and cellular factors in COVID-19

20

20220223

111145

Weng Ching-Fu

Respiratory Therapy & Chest medicine, Hsinchu Cathay General Hospital

SLC7A5 in lung cancer as therapeutic target and drug screen platform with analysis of clinical prognostic relevance

100

20220223

111146

Yi-Hsin Yang

National institute of cancer research, National Health Research Institutes

Investigate metabolic complications in liver cancer patients treated with target therapies

6000

20220223

111147

Chun Liang Shih

Panion & BF Biotech inc.

Evaluation of the detection performance of Vstrip COVID-19 S-RBD Antibody Rapid Test for sera of patients infected with COVID-19 variant strains

18

20220421

111148

Yi-Wen Huang

CRC, TMUH

To explore the difference in molecular signature between virus and steatosis-related liver cancer

1050

20220617

111149

CHI-Cheng Huang

Comprehensive Breast Health Center, Taipei Veterans General Hospital

New drug development guided from biomedical big data

2

20220617

111150

Chao-Lun Lai

Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch

Comparison of neutralizing antibody levels against SARS-CoV-2 variants before and after the third SARS-CoV-2 booster shot

55

20220617

111151

Mei-Hsuan Lee

Institute of Clinical Medicine, National Yang Ming Chiao Tung University

Genetic susceptibility and the associated risk of cholangiocarcinoma and non-hepatitis B and non-hepatitis C hepatocellular carcinoma

300

20220718

111152

Tsai-Yuan Hsieh

Division of Gastroenterology, Tri-Service General Hospital

To investigate the regulatory mechanisms of CRNDE gene in hepatocellular carcinoma and the clinical significance of its associated molecular expression

50

20220831

111153

Shih-Hsien Hsu

Graduate Institute of Medicine, Kaohsiung Medical University

ISX-induced hepatic steatosis impacts the progression of COVID-19

100

20220831

111154

Shao-Chun Wang

College of Medicine/ Research Center for Cancer Biology/ Center for Molecular Medicine, China Medical University & Hospital Taiwan, R.O.C.

Developing novel tumor and blood biomarkers of marker-guided effective cancer therapies

208

20220831

111155

Shu-Chi Wang

Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University

Investigation of exosomal DANCR in predicting of HCC recurrence in HCV-related HCC post curative therapy, mechanism of action, and the feasibility on precision medicine application.

200

20220831

111156

Chao-Wei Hsu

Department of Hepatology and Gastroenterology, Chang Gung Memorial Hospital

Analyses of Hepatitis Delta Virus Mutants Isolated from Hepatocellular Carcinoma Patients Co-infected with Hepatitis B/D Viruses

4

20220831

111157

Hsiang-Tsui Wang

Department of Pharmacology, National Yang Ming Chiao Tung University

Using nano-imaging approaches to reveal the interplay of SARS-CoV-2 spike protein with cellular receptors and SARS-CoV-2 spike protein-induced cellular responses

250

20221017

111158

Lai, Tsung-Ching

Division of Pulmonary Medicine, Taipei Municipal Wanfang Hospital

Investigate the contradictory role and function of sphingosine kinases (SPHK1 and SPHK2) in lung adenocarcinoma

86

20221017

111159

Hsin-Ling Hsu

Institute of Molecular and Genomic Medicine, National Health Research Institutes

Roles of microRNA-34a and MCT-1 in lipid metabolism during macrophage reprogramming and carcinogenesis

30

20230222

111160

Donching Lee

TAQKEY Science Co., Ltd.

DNA methylation for hepatocellular carcinoma

25

20221216

111161

Yu-Li Liu

Center for Neuropsychiatric Research, National Health Research Institutes

Preliminary study on the correlation between brain nerve damage and biomarkers for disease symptoms in patients with COVID

200

20221216

111162

Tian-Lu Cheng

Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University

Precising the pro-antibody engineering by computer simulation, X-ray crystallography and cryogenic electron microscopy to comprehensively improve the disease selectivity and reduce the side effects of antibody drugs

50

20221216

111163

Pei-Jer Chen

Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine

Contribution of HDV in HBV-induced insertional mutagenesis in HBV, HDV-related HCC

70

20221216

111164

Cherng Yih-Giun

Superintendent Office,Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare

Identification of Targetable mediators involving in PP1R15B Pathway to Overcome Resistance to Lenvatinib in Drug-Tolerant Persister Liver Cancer

30

20221216

111165

Chau-Ting Yeh

School of medicine, Chang-Gung University

Analysis of the role of ApoC1 in hepatocarcinogenesis

200

20221216

111166

Jo Ting Tsai

Radiation Oncology, Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare

A mechanism Study of the Interplay between pre-mRNA-SRSF1 and XIRP2 in Radiation Resistance and Metastasis of Hepatocellular Carcinoma

30

20221216

112167

Ho, Hsiang-Ling

Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital

To validate the efficacy of microbes infectious and cancer-related biomarkers in vitro diagnostic devices_NSCLC ALK

20

Under Review

112168

Hui-Lin Wu

Hepatitis Research Center, National Taiwan University Hospital

Study on the early recurrence of HBV-associated hepatocellular carcinoma: with emphasis on the molecular mechanisms and clinical implications of a novel metastatic tumor antigen 1 spliced variant, MTA1dE4 hepatocellular carcinoma: with emphasis on the molecular mechanisms and clinical implications of a novel metastatic tumor antigen 1 spliced variant, MTA1dE4

150

20230222

112169

En-Chi Hsu

Institute of Molecular and Genomic Medicine, National Health Research Institutes

Develop Liquid Biopsy-Based Exosomal Correlative Signature Utilizing Oncoprotein-microRNA-circRNA Functional Networks for Early Detection of Liver Cancer

150

Under Review

112170

Chao-Wei Hsu

Department of Hepatology and Gastroenterology, Chang Gung Memorial Hospital

Analyses of Hepatitis Delta Virus Mutants Isolated from Hepatocellular Carcinoma Patients Co-infected withHepatitis B/D Viruses

70

20230222

112171

Hu Ching-Wen

Nursing department, Tungs’ Taichung MetroHarbor Hospital

Clinical characteristics of mild COVID-19 with DM patients in Taiwan

250

20230222

112172

Shih-Cheng Chen

National Institute Cancer Research, National Health Research Institutes

Validation of genetic variations associated to severe Covid-19 from NBCT data

250

20230419

112173

Yu-Li Liu

Center for Neuropsychiatric Research, National Health Research Institutes

Preliminary study on the correlation between brain nerve damage and biomarkers for disease symptoms in patients with COVID

200

20230419

112174

Ren-Hua Chung

Institute of Population Health Sciences, National Health Research Institutes

Multi-omics analysis to identify novel immune genes for triple-negative breast cancer and functionally validating their roles in cancer subtyping, tumorigenesis and immune microenvironment

13

20230419

112175

Jer-Wei Chang

Precision Medicine and Informatics, Institute Drug Evaluation Platform, Development Center for Biotechnology

Development of Different Cancers Biomarkers for Precision Medicine with Big Data Analyses

26

20230628

112176

Tang- Yuan Chu

Department of Obstetric & Gynecology, Tzu Chi Hospital, Hualien

FE25 cell transformation as a serum bioassay to detect cancers and estimate tumor load: a validation study and characterization of the transformation activity

114

20230822

112177

Hung-Chih Yang

Internal Medicine, NTUH

Comprehensive Delineation of Oncofetal Ecosystem in Hepatocellular Carcinoma after Hepatectomy

270

20230822

112178

Dong-Hao Chen

Research and evelopment department, Sun Jet Biotechnology Inc.

Development of methodology for lung cancer biomarker

130

20231026

112179

Wen-Hui Su

Department of Biomedical Sciences, Chang Gung University

Feasibility Assessment of Polygenic Risk Score-Stratified Screening in Hepatocellular Carcinoma

600

20231026

112180

Yang-His Tsai

Integrative Genomic Diagnostics, Chung-Yi Medical Laboratory

Pan Cancer Molecular Biomarker in Solid Tumors Validation Plan

29

20231213

112181

Kun-Yu Lai

Department of Optics and Photonics, National Central University

High throughput Raman spectroscopy: A new DNA testing for cancers and cord blood

10

20231213

112182

Yu-Li Liu

Center for Neuropsychiatric Research, National Health Research Institutes

Preliminary study on the correlation between brain nerve damage and biomarkers for disease symptoms in patients with COVID

200

20231213

112183

Yu-Li Liu

Center for Neuropsychiatric Research, National Health Research Institutes

Preliminary study on the correlation between brain nerve damage and biomarkers for disease symptoms in patients with COVID

250

20231213

113184

Huamei Chang

Research & Development, SP BioMED Co. Ltd.

Polygenic risk score for early onset breast cancer of Taiwan

13

20240227

113185

Joe Yeh

Office of the CEO, aetherAI Co., Ltd.

Classification model of me staining in lung cancer and urothelial carcinoma

30

20240227

113186

Guan-Da Syu

Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University

Antibody Profiling of COVID-19 Using Coronavirus Protein and Peptide Microarray

60

20240227

113187

Hui-Lin Wu

Hepatitis Research Center, National Taiwan University Hospital

Investigating the roles and molecular mechanisms of the major vault protein (MVP) in hepatocellular carcinoma induced by HBV (hepatitis B virus) and HBV with concurrent metabolic dysfunction-associated steatotic liver disease (MASLD)

200

20240418

113188

Tung-Hung Su

Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital

Clinical utility of laminin γ2 monomer (LG2m) in prognosing extrahepatic spread (EHS) of tumor in early to intermediate stage hepatocellular carcinoma (HCC) patients

240

20240418

113189

Ming-Shiu Hung

Institute of Biotechnology & Pharmaceutical Research, National Health Research Institutes

Orphan G protein-coupled receptor in the pathogenesis of liver fibrosis

15

20240614

113190

Chau Ting Yeh

Gastroenterology,Hepatobiliary and Biology, Chang Gung Memorial Hospital,Linkou

Genetic and virological factors in the cirrhotic liver in association with hepatocellular carcinoma postoperative prognosis

30

20240614

113191

Shiou-Hwei Yeh

Graduate Institute of Microbiology, National Taiwan University College of Medicine

New immunotherapies for chronic hepatitis B and hepatocellular carcinoma — Subproject 4: Driver mutations in HBV-infected hepatocytes enabling immune-escape and tumorigenesis: mechanisms and therapeutic targets

185

20240813

113192

Kuo-Sheng Liao

Department of Pathology, Taoyuan General Hospital, Ministry of Health and Welfare

The role of protein phosphatase deficiency in liver cell junction defects and cancers

80

20240813

113193

Ming-Hui Lin

Department of Gastroenterology, Taoyuan General Hospital, Ministry of Health and Welfare

Establishing a zebrafish model to study the molecular mechanisms of NASH and NASH associated HCC toward develop therapies

150

20240813

113194

YU-SHAN WANG

General Manager Office,UniPharma Co.,Ltd.

Analysis of the differential expression of the DR-70 tumor marker in various cancer patients compared to a healthy population, utilizing serum samples from the National Biobank Consortium of Taiwan

114

20240813

113195

Mei-Hsuan Lee

Institute of Clinical Medicine, National Yang Ming Chiao Tung University

Identifying Protein Biomarkers for Early Detection of Hepatobiliary Cancers

400

20241022

113196

Ming-Wei Lai

Pediatric,Linkou Chang Gung Memorial Hospital

Investigating Extracellular Vesicles and Their Role in Hepatitis B Virus-Related Liver Disease Progression

40

20241022

113197

Ming-Wei Lai

Pediatric,Linkou Chang Gung Memorial Hospital

Identification and characterization of novel biomarkers of response to targeted therapy in patients with advanced HBV-related hepatocellular carcinoma

40

20241022

113198

Wey-Ran Lin

Gastroenterology, Linkou Chang Gung Memorial Hospital

To identify the potential biomarkers in advanced hepatocellular carcinoma: using circulating and exosomal mitochondrial DNA and their mutations

40

20241023

113199

Ya-Hsuan Chang

Institute of Molecular and Genomic Medicine, National Health Research Institute

Derivation and validation of prognostic prediction models in patients with intermediate and advanced hepatocellular carcinoma based on GALNT14 genotype

4000

20241022

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